Table 1.
Samples, family, and herbarium number a | Traditional treatment | Area of plant collection | Known bioactive or potentially active compounds | Screened biological activities of the crude extracts and known bioactive compounds |
---|---|---|---|---|
Allanblackia gabonensis Pellegr. (Clusiaceae); 17275SRF/Cam | Dysentery, cold, toothache [13]; pain, rheumatism, inflammations [14, 15]. | Lebialem, South West region of Cameroon; (4°10′N 9°14′E/4.167°N 9.233°E) | Not reported | Crude extracts: Analgesic and anti-inlammatory effect of aqueous extract of the stem bark [14]; crude methanol fruits extracts (40 μg/mL) showed to inhibit growth of CCRF-CEM leukemia cells at about 50 % [16]. |
Gladiolus quartinianus A. Rich (Iridaceae); 17260/SRF/Cam | Infections of the skin, gut, urogenital system, and upper respiratory tract [17], gonorrhea, infectious conditions, constipation and dysentery [18]. | Lebialem, South-West region of Cameroon; (4°10′N 9°14′E/4.167°N 9.233°E) | Not reported | Methanol crude extract was reported to possess moderate to significant anticancer activity (IC50: 29.60 to10.57 μg/mL) against drug-resistance cancer cell lines [16] |
Combretum molle R. Br. ex G. Don (Combretaceae); 33311/ HNC | Fever, abdominal pains, convulsion, worm infections, human immunodeficiency virus (HIV)/acquiredimmune deficiency syndrome (AIDS) related infections [19]; hookworm, snake bite, leprosy, dysentery, general body swellings, arthritic and other inflammatory conditions, sterility, constipation [20, 21]; Parasitic, protozoan, infectious diseases [22], malaria [23] | University of Dschang, West region of Cameroon; (6°30′N 10°30′E/6.500°N 10.500°E) | Mollic acid glucoside [21]); β-D-glucopyranosyl 2α,3β,6β-trihydroxy-23-galloylolean-12-en-28-oate,combregenin, arjungenin, arjunglucoside I, and combreglucoside [24] . | Crude extracts were evaluated for: antibacterial activity [25–27]; antimycobacterial [28]; antifungal effects [29]; antimalarial [30]; anthelmintic activities [31]; anti-HIV by inhibition of ribonuclease-H [19]; Cytotoxic effects against T-24 bladder cancer cells [32]; Anti-inflammatory activity [24]; in vitro anticholinesterase and inhibitory effects on Rabbit Breathing [33]. Compounds: mollic acid glucoside (MAG) showed analgesic, anti-inflammatory properties in mice and rats [21], cardiovascular effect [34]; hypoglycaemic effect [35]; Punicalgin and CM-A, two isolated tannins were assessed for their anti-HIV activity against human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) [36]. |
aPlants were identified at the Cameroon National Herbarium (HNC)