. 2015 Jun 1;19(6):295–302. doi: 10.1089/gtmb.2014.0292

Table 3.

The Frequency of CpG Island Hypermethylation in Tumor and Nontumorous Liver Samples from HCC, Cirrhotic Liver Samples Without Concurrent HCC, and Normal Liver Samples

Diagnosis	No. of cases	No. of cases methylated for at least one gene (%)^a	No. of cases methylated for at least two genes (%)^a	No. of cases methylated for at least three genes (%)^a	Average no. of methylated gene^b
Tumor tissue	34	34 (100)	33 (97.06)^c	27 (79.41)^d	3.00±0.74^e
Nontumor tissue	34	32 (94.12)	22 (64.71)^c	12 (35.30)^d	2.03±1.17^e
LC	10	10 (100)	8 (80)	5 (50)	2.40±0.97
Normal liver	4	0	0	0	0^e

p-Value results for other tests are not significant.

^{^a}

Analyzed by χ² test or Fisher's exact test, as appropriate.

^{^b}

Analyzed by one-way ANOVA test.

^{^c}

p=0.001, tumor versus nontumorous tissue.

^{^d}

p<0.001, tumor versus nontumorous tissue.

^{^e}

p<0.001, tumor versus nontumorous tissue, nontumorous versus normal liver tissue, LC versus normal liver tissue.

ANOVA, analysis of variance.