Table 3. Associations between Sirtuins and Tumour Pathological Parameters.

SIRTUIN	Cellular Localisation	Prognostic Factor	p-Value
SIRT3	Nuclear	Tumour Differentiation	0.05
		Tumour Grade	0.015
	Cytoplasmic	Tumour Grade	0.035
SIRT5	Nuclear	Tumour Size (<30mm)	0.038
		Vascular Invasion	0.042
		Lymphatic Invasion	0.033
SIRT7	Nuclear	Margin Involvement	0.017
	Cytoplasmic	Margin Involvement	0.039
		Tumour Grade	0.032

Table showing the significant Chi Squared results between low/high Sirtuin expression and prognostic factors, with corresponding p-values.