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. 2015 Jun 5;8(3):176–184. doi: 10.1016/j.tranon.2015.03.009

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© 2015 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Quantification of the mean percentage of Gd-permeable (black) and Gd-permeable (white) tumors (± SEM). The percentage of Gd-permeable or Gd-impermeable tumors was significantly different between groups (F_2,12 = 22.18, P < .0001). All SUM190-BR3 and most JIMT-1-BR3 tumors were Gd permeable, whereas only 63.6% of MDA-MB-231-BR-HER2 tumors display BTB permeability to Gd. Post hoc Tukey tests showed that the MDA-MB-231-BR-HER2 had a significantly different proportion of Gd-permeable and Gd-impermeable tumors compared to the JIMT-1-BR3 or SUM190-BR3 models. No other significant differences in permeability were observed.