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Representative images of CD31 (top) and CD105 (bottom) staining in SUM190-BR3, JIMT-1-BR3, and MDA-MB-231-BR-HER2 models. Staining patterns were qualitatively assessed for the distribution of endothelial cells and proliferative endothelial cells in tumor regions. Different staining patterns are evident between models; however, there is no obvious difference in the staining patterns between Gd-permeable and Gd-impermeable metastases within the MDA-MB-231-BR-HER2 model.
