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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Histochem Cell Biol. 2015 Jan 8;143(6):565–574. doi: 10.1007/s00418-014-1304-0

Figure 4. CX3CR1 silencing impairs THP-1 monocyte adherence to BeWo cells.

Figure 4

Transfection of BeWo cells with CX3CR1 targeting siRNA (siCX3CR1) significantly reduced CX3CR1 mRNA (a) and protein (b) levels after 24h, when compared to cells transfected with non targeting control. Silencing of CX3CR1 expression in THP-1 monocytes significantly decreased adhesion to Forskolin stimulated BeWo cells, but only marginally reduced binding to DMSO treated BeWo cells (c). Data are presented as mean ± SEM from three independent BeWo cell experiments performed in triplicates. *p<0.05, ***p<0.001