Skip to main content
. Author manuscript; available in PMC: 2015 Nov 28.
Published in final edited form as: AIDS. 2014 Nov 28;28(18):2701–2709. doi: 10.1097/QAD.0000000000000497

Table 2. Protective efficacy against incident episodes of malaria stratified by age.

Treatment
arm		 Randomization to 24 months of age
 Randomization to 16 months of age
 17 to 24 months of age
Number
of cases		 PYAR1 Incidenc
e per
PYAR1 		PE2 (95% CI) p value Incidence
per
PYAR1 		PE2 (95% CI) p value Incidence
per
PYAR1 		PE2 (95% CI) p value
Control 240 38.2 6.28 reference - 5.42 reference - 7.04 reference -
Monthly SP 182 40.4 4.50 9% (−35 to 38) 0.65 3.72 2% (−64 to 42) 0.93 5.22 14% (−29 to 43) 0.47
Daily TS 116 40.6 2.86 49% (23 to 66) 0.001 1.70 63% (34 to 79) 0.001 3.79 42% (12 to 62) 0.01
Monthly DP 82 44.7 1.83 69% (53 to 80) <0.001 0.90 84% (69 to 92) <0.001 2.67 61% (39 to 75) <0.001
1

PYAR = person-year at risk

2

PE = protective efficacy adjusted for age at randomization and incidence of malaria prior to randomization