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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Gene Ther. 2014 Jul 24;21(10):913–920. doi: 10.1038/gt.2014.65

Figure 3.

Figure 3

Histological transduction of feline and murine outer retinas. (a) Feline retinal sections co-labeled with a GFP antibody and cone arrestin antibody show the predominance of cone transduction for each of the vectors. rAAV2/2 eyes all showed inflammation, thereby affecting section quality, as evidenced in the rAAV2/2 images. (b) In murine retinas, rAAV 2/5, 2/8 and 2/9 vectors transduced rods, cones and RPE, whereas rAAV 2/2 only transduced the RPE. Scale bar=50 µm. CAR, cone arrestin labeling; DAPI, nuclear counterstain; INL, inner nuclear layer; ONL, outer nuclear layer.