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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Am J Gastroenterol. 2015 May 26;110(6):915–920. doi: 10.1038/ajg.2015.150

Table 1.

Eligible HLA genotypes in the TEDDY study

Letter Full genotype Abbreviated genotype
A DRB1*04-DQA1*03-DQB1*03:02/
DRB1*03-DQA1*05-DQB1*02:01		 DR4-DQ8/DR3-DQ2
B DRB1*04-DQA1*03-DQB1*03:02/
DRB1*04-DQA1*03-DQB1*03:02		 DR4-DQ8/DR4-DQ8
C DRB1*04-DQA1*03-DQB1*03:02/
DRB1*08-DQA1*04-DQB1*04:02		 DR4-DQ8/DR8-DQ4
D DRB1*03-DQA1*05-DQB1*02:01/
DRB1*03-DQA1*05-DQB1*02:01		 DR3-DQ2/DR3-DQ2
E DRB1*04-DQA1*03-DQB1*03:02/
DRB1*04-DQA1*03-DQB1*02:02		 DR4-DQ8/DR4*
F DRB1*04-DQA1*03-DQB1*03:02/
DRB1*01-DQA1*01-DQB1*05:01		 DR4-DQ8/1
G DRB1*04-DQA1*03-DQB1*03:02/
DRB1*13-DQA1*01-DQB1*06:04		 DR4-DQ8/13
I DRB1*04-DQA1*03-DQB1*03:02/
DRB1*09-DQA1*03-DQB1*03:03		 DR4-DQ8/9
J DRB1*03-DQA1*05-DQB1*02:01/
DRB1*09-DQA1*03-DQB1*03:03		 DR3-DQ2/9

HLA, human leukocyte antigen; TEDDY, The Environmental Determinants of Diabetes in the Young.

Genotypes A, B, C, and D confer general population eligibility but exclude DRB1*0403. Genotypes A through J confer eligibility to a first-degree relative with type 1 diabetes. Where DQB1*03:02 is noted, either this allele or DQB1*03:04 is allowed (13).