. Author manuscript; available in PMC: 2015 Dec 1.

Published in final edited form as: Am J Gastroenterol. 2015 May 26;110(6):915–920. doi: 10.1038/ajg.2015.150

Table 3.

Proportions of nested case–control groups and replication cohort, at the time of data freeze

	n	tTGA (%)	Female (%)	Caucasian (%)	DR3-DQ2/ DR3-DQ2 (%)
Cases	248	100	61.3	95.6	52.8
Controls	248	0	61.3	97.2	24.2
Replication cohort	4,514	9.6	47.34	100	20.8

tTGA, tissue transglutaminase autoantibody. The case–control group included 232 subjects with DR3-DQ2/DR4-DQ8, 51 with DR4-DQ8/DR4-DQ8, 18 with DR4-DQ8/DR8-DQ4, and 191 with DR3-DQ2/DR3-DQ2.

Cases were children with celiac disease autoimmunity and defined as being persistently positive to tTGAs.