Table 5.
Results of Cox proportional hazards model (n=4,514; 432 failures), with HLA-DPB1*04:01 being the only continuous variable in the model
| Covariate | Hazard ratio (95% CI) | P-value |
|---|---|---|
| HLA-DPB1*04:01 | 0.84 (0.73–0.96) | 0.013 |
| Country | ||
| Finland | 1.35 (1.04–1.74) | 0.024 |
| Germany | 1.04 (0.66–1.62) | 0.872 |
| Sweden | 1.38 (1.10–1.73) | 0.006 |
| Sex (female) | 1.71 (1.41–2.07) | 0.000 |
| HLA category | ||
| B | 0.61 (0.46–0.83) | 0.001 |
| C | 0.19 (0.12–0.32) | 0.000 |
| D | 2.29 (1.86–2.82) | 0.000 |
CI, confidence interval: HLA, human leukocyte antigen.
Reference country is the USA, reference sex is male, and reference HLA category is A (see Table 1).