Skip to main content
. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Exp Hematol. 2015 Apr 24;43(7):537–545.e11. doi: 10.1016/j.exphem.2015.03.006

Figure 1. A schematic of the research plan.

Figure 1

Donor mice received 5FU and bone marrow cells were harvested five days later. These cells were infected with MIG-JAK2V617F and injected into lethally irradiated recipient mice. Dosing with BMS-911543 began when the average hematocrit exceeded 70% and continued for 42 days. VC - vehicle control, LD - low dose (3 mg/kg), HD - high dose (10 mg/kg), PD - pharmacodynamics, CBC - complete blood count, GFP - green fluorescent protein