Table 3. Selected list of expressed genes involved in inflammatory response after intratracheal instillation with SWCNTs.
| Gene | L-SWCNT |
H-SWCNT |
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GenBank | name | 3 d | 7 d | 30 d | 90 d | 180 d | 365 d | 754 d | 3 d | 7 d | 30 d | 90 d | 180 d | 365 d | 754 d | Description |
| NM_001008515 | C1qa | 0.8 | 1.2 | 1.1 | 0.7 | 0.3 | 0.0 | 0.4 | 0.8 | 1.6 | 1.2 | 1.1 | 1.0 | 0.3 | 0.4 | Complement component 1, q subcomponent, A chain |
| NM_016994 | C3 | 1.5 | 1.0 | 1.9 | 1.4 | 0.5 | 0.1 | −0.1 | 1.6 | 1.4 | 1.5 | 1.9 | 1.3 | 0.1 | −0.2 | Complement component 3 |
| NM_012516 | C4bpa | 1.3 | 1.6 | 1.8 | 1.3 | 0.4 | 0.3 | 0.1 | 1.4 | 2.2 | 1.6 | 1.5 | 1.1 | 0.3 | 0.2 | Complement component 4 binding protein, alpha |
| NM_016995 | C4bpb | 0.6 | 1.0 | 1.3 | 0.9 | 0.3 | 0.5 | −0.1 | 0.9 | 1.2 | 1.2 | 1.3 | 0.5 | 0.6 | −0.2 | Complement component 4 binding protein, beta |
| NM_031530 | Ccl2 | 2.0 | 2.4 | 2.4 | 2.4 | 0.1 | −0.1 | 0.1 | 2.5 | 3.2 | 2.4 | 2.7 | 1.1 | 0.2 | 0.4 | Chemokine (c-c motif) ligand 2 |
| NM_013025 | Ccl3 | 1.1 | 1.3 | 1.5 | 1.2 | 0.2 | −0.3 | −0.4 | 1.3 | 1.7 | 1.3 | 1.3 | 0.9 | 0.0 | −0.2 | Chemokine (c-c motif) ligand 3 |
| NM_053858 | Ccl4 | 0.6 | 0.9 | 1.3 | 0.6 | 0.0 | −0.1 | −0.2 | 0.7 | 1.0 | 0.7 | 0.6 | 0.4 | −0.1 | −0.1 | Chemokine (c-c motif) ligand 4 |
| NM_031116 | Ccl5 | 0.2 | −0.1 | 0.2 | 0.0 | −0.3 | −0.1 | −0.1 | 0.0 | 0.0 | −0.2 | −0.3 | 0.1 | 0.0 | −0.2 | Chemokine (c-c motif) ligand 5 |
| NM_001007612 | Ccl7 | 1.9 | 2.8 | 3.2 | 2.2 | 0.1 | −0.4 | −0.1 | 2.5 | 3.7 | 3.3 | 2.9 | 1.5 | 0.0 | 0.4 | Chemokine (c-c motif) ligand 7 |
| NM_001012357 | Ccl9 | 0.5 | 0.9 | 1.6 | 1.0 | 0.6 | 0.1 | 0.2 | 0.3 | 1.0 | 1.3 | 1.2 | 1.1 | 0.1 | 0.5 | Chemokine (c-c motif) ligand 9 |
| NM_001105822 | Ccl12 | 1.6 | 1.8 | 2.0 | 2.1 | −0.6 | −0.6 | 0.3 | 2.3 | 2.7 | 1.8 | 2.2 | 0.3 | −0.8 | 0.3 | Chemokine (c-c motif) ligand 12 |
| NM_057151 | Ccl17 | 2.1 | 1.7 | 1.3 | 1.0 | 0.1 | −0.8 | 0.0 | 2.3 | 2.0 | 0.8 | 1.4 | 0.7 | −0.9 | 0.4 | Chemokine (c-c motif) ligand 17 |
| NM_057203 | Ccl22 | 4.0 | 2.7 | 2.3 | 1.7 | 0.8 | −0.2 | −0.5 | 4.0 | 3.4 | 2.0 | 2.4 | 1.6 | 0.2 | 0.3 | Chemokine (c-c motif) ligand 22 |
| NM_030845 | Cxcl1 | 1.7 | 0.6 | 0.3 | 0.7 | 0.2 | −0.4 | 0.5 | 1.8 | 0.6 | −0.2 | 0.7 | 0.6 | −0.7 | 0.3 | Chemokine (c-x-c motif) ligand 1 |
| NM_053647 | Cxcl2 | 1.8 | 0.8 | 0.3 | 1.4 | 0.3 | −0.7 | 0.3 | 2.2 | 1.5 | 0.2 | 1.5 | 1.0 | −0.8 | 0.6 | Chemokine (c-x-c motif) ligand 2 |
| NM_138522 | Cxcl3 | 1.6 | 0.7 | 1.1 | 0.7 | 0.1 | 0.2 | 0.1 | 1.8 | 1.1 | 0.8 | 1.2 | 0.7 | −0.2 | −0.1 | Chemokine (c-x-c motif) ligand 3 |
| NM_022214 | Cxcl5 | 1.3 | 0.6 | 1.6 | 1.9 | −0.8 | −0.6 | −0.1 | 1.7 | 0.6 | 2.1 | 2.2 | 0.0 | 0.3 | −0.2 | Chemokine (c-x-c motif) ligand 5 |
| NM_053958 | Ccr3 | 1.0 | 0.3 | 0.2 | −0.8 | 0.8 | 0.1 | −0.8 | 1.3 | 0.7 | −0.1 | −0.7 | 0.6 | 0.2 | 0.1 | Chemokine (c-c motif) receptor 3 |
| NM_133532 | Ccr4 | 2.0 | 3.4 | 1.8 | 0.8 | 0.0 | −0.3 | 0.4 | 1.8 | 3.6 | 1.8 | 1.2 | 0.2 | 0.2 | −0.3 | Chemokine (c-c motif) receptor 4 |
| NM_053288 | Orm1 | 3.6 | 3.4 | 3.3 | 3.7 | 2.6 | 0.2 | −0.7 | 3.9 | 3.6 | 2.9 | 4.7 | 4.4 | 0.7 | 0.8 | Orosomucoid 1 |
Numerical values represent gene expression log-fold change compared to control levels. Log fold changes with p values less or equal than 0.05 are shown in italics.