Table 4. Selected list of expressed genes involved in response to oxidative stress and apoptosis after intratracheal instillation with SWCNTs.

	Gene	L-SWCNT							H-SWCNT
Genbank	name	3 d	7 d	30 d	90 d	180 d	365 d	754 d	3 d	7 d	30 d	90 d	180 d	365 d	754 d	Description
NM_030826	Gpx1	0.0	0.0	0.4	0.1	0.0	0.1	0.1	0.1	0.4	0.3	0.1	0.3	0.1	−0.1	Glutathione peroxidase 1
NM_022525	Gpx3	−0.2	−0.5	0.1	−0.5	−0.1	−0.2	0.1	−0.2	−0.6	−0.1	−0.3	0.2	−0.2	0.0	Glutathione peroxidase 3
NM_012962	Gss	0.3	−0.2	0.5	0.1	0.1	0.0	0.1	0.3	0.2	0.4	0.4	0.4	0.0	0.0	Glutathione synthetase
NM_012580	Hmox1	0.5	0.6	1.5	1.0	0.4	0.1	−0.7	0.6	1.1	1.5	1.4	0.9	0.3	0.4	Heme oxygenase (decycling) 1
NM_017050	Sod1	0.1	−0.2	0.2	−0.2	−0.1	−0.1	0.0	0.1	0.1	−0.1	−0.1	0.2	−0.2	0.0	Superoxide dismutase 1
NM_017051	Sod2	1.1	1.0	1.3	1.0	0.1	−0.1	0.1	1.1	1.1	1.3	1.0	0.4	0.1	0.2	Superoxide dismutase 2, mitochondrial
NM_012762	Casp1	−0.1	0.0	0.0	−0.2	−0.1	0.0	0.0	−0.1	0.0	−0.2	−0.4	0.0	0.2	0.0	Caspase 1
NM_022522	Casp2	0.1	0.0	0.0	−0.1	0.0	0.1	0.0	0.0	0.2	−0.2	−0.2	0.2	0.1	0.0	Caspase 2
NM_012922	Casp3	−0.1	−0.1	0.0	0.0	0.1	0.1	0.1	−0.1	−0.1	0.0	−0.1	0.0	0.2	0.0	Caspase 3
NM_053736	Casp4	0.4	0.3	0.2	0.1	−0.2	0.1	0.1	0.3	0.6	0.1	0.4	0.1	0.1	0.0	Caspase 4
NM_022260	Casp7	0.1	0.1	0.1	−0.1	−0.3	0.1	0.0	0.1	0.3	−0.1	−0.2	0.0	0.1	0.0	Caspase 7
NM_022277	Casp8	0.3	0.2	0.4	−0.1	0.1	0.1	0.0	0.2	0.3	0.1	−0.2	0.3	0.2	−0.1	Caspase 8
NM_130422	Casp12	0.1	−0.1	0.0	−0.2	0.0	0.0	0.1	0.1	0.1	−0.3	−0.2	0.1	−0.2	0.0	Caspase 12
NM_012520	Cat	0.2	−0.3	0.6	−0.2	0.2	0.2	0.2	0.1	0.2	0.3	0.0	0.6	0.1	0.1	Catalase
NM_130741	Lcn2	2.8	2.7	3.6	2.9	1.3	0.8	0.1	3.0	3.2	3.3	3.5	2.5	0.9	0.2	Lipocalin 2

Numerical values represent gene expression log fold change compared to control levels. Log fold changes with p values less or equal than 0.05 are shown in italics.