Table II.
Characteristics of 56 celiac disease antibody-positive participants according to whether they were diagnosed with celiac disease or not.
| Participants who completed clinical evaluation and biopsy |
|||
|---|---|---|---|
| All antibody-positive participants | Celiac disease not confirmed | Diagnosed with celiac disease | |
| Number | 56 | 32 | 8 |
| Mean age in years | 55.8 (26–74) | 56.3 (26–74) | 53.3 (29–73) |
| Antibody positivity | |||
| IgA-TTG | 13 (23.2) | 2 (6.3) | 7 (87.5) |
| IgA-DGP | 47 (83.9) | 27 (84.4) | 5 (62.5) |
| IgG-DGP | 12 (21.4) | 5 (15.6) | 5 (62.5) |
| IgG-TTG | 0 (0) | 0 (0) | 0 (0) |
| HLA type | |||
| + DQ2/ − DQ8 | 28 (50.0) | 14 (43.8) | 6 (75.0) |
| + DQ2/ + DQ8 | 4 (7.1) | 2 (6.3) | 2 (25.0) |
| − DQ2/ + DQ8 | 8 (14.3) | 5 (15.6) | 0 (0) |
| − DQ2/ − DQ8 | 16 (28.6) | 11 (34.4) | 0 (0) |
| Marsh classification | |||
| 0 | - | 30 (93.8) | 0 (0) |
| 1 | - | 2 (6.3) | 1 (12.5) |
| 2 | - | 0 (0) | 0 (0) |
| 3A | - | 0 (0) | 2 (25.0) |
| 3B | - | 0 (0) | 3 (37.5) |
| 3C | - | 0 (0) | 2 (25.0) |
| Breath tests | |||
| Lactose intolerance | - | 1 | 0 |
| Glucose intolerance | - | 0 | 0 |
| BMD | n = 33 | n = 26 | n = 7 |
| Total lumbar spine | |||
| t-score | - | −0.27 (1.82) | −0.16 (1.60) |
| BMD (g/cm2) | - | 1.04 (0.20) | 1.05 (0.18) |
| Total left hip | |||
| t-score | - | −0.50 (1.13) | −0.21 (0.78) |
| BMD (g/cm2) | - | 0.93 (0.17) | 0.95 (0.10) |
| Total right hip | |||
| t-score | - | −0.52 (1.12) | −0.16 (0.97) |
| BMD (g/cm2) | - | 0.92 (0.16) | 0.96 (0.13) |
| Osteoporosis | |||
| Osteoporosis | - | 3 | 0 |
| Osteopenia | - | 9 | 2 |
Abbreviations: BMD = Bone mineral density; HLA = Human lymphocyte antigen; IgA-TTG = IgA antibody to tissue transglutaminase; IgA-DGP = IgA to deamidated gliadin peptide; IgG-DGP = IgG to deamidated gliadin peptide.