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. 2015 Jun 12;6(1):119. doi: 10.1186/s13287-015-0110-5

Fig. 5.

Fig. 5

Effect of ROS scavengers on the autophagic proteolysis in PG-3T3L1 cells. a, b Western blot analysis of LC3 demonstrates a significant reduction in the LC3-II/LC3-I ratio in PG-3T3L1 cells incubated with 10 mM N-acetyl-cysteine (NAC) for 1 hour when compared with basal conditions. c, d Western-blot analysis of LC3 demonstrates a significant reduction in the LC3-II/LC3-I ratio in PG-3T3L1 cells incubated with 10 μM MitoTempo for 1 hour when compared with basal conditions. LC3 light chain 3, PG progerin