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. 2015 Jun 24;16(1):74. doi: 10.1186/s12931-015-0234-2

Table 1.

Identified proteins in control and NSCLC tissues by MS analysis

Protein Gene Gene ID MWa Mascot Scoreb Mascot Scoreb
[Peptide]c [Peptide]c
NSCLC Control
lactoferrin precursor LTF 12083188 80214 946 [15] 298 [5]
transferrin TF 37747855 79310 581 [9] 940 [15]
78 kDa glucose-regulated protein precursor HSPA5 16507237 72402 507 [8] 503 [8]
moesin MSN 4505257 67892 412 [8] 396 [7]
myeloperoxidase, isoform CRA_d MPO 119614879 76923 331 [6] 73 [1]
protein disulfide-isomerase A4 precursor PDIA4 4758304 73229 191 [3] 128 [2]
glyceraldehyde-3-phosphate dehydrogenase GAPDH 31645 36201 581 [9] 375 [6]
annexin A2 isoform 2 ANXA2 18645167 38808 975 [16] 504 [10]
annexin A1 ANXA1 4502101 38918 587 [8] 522 [7]
L-lactate dehydrogenase A isoform 1 LDHA 5031857 36950 391 [7] N. D.d
aldolase A ALDOA 28614 39706 240 [4] 65 [1]
peroxiredoxin-1 PRDX1 4505591 22324 158 [3] 253 [5]
Aldo-keto reductase family 1 member C4 AKR1C4 308153631 37442 155 [3] N. D.d
60S acidic ribosomal protein P0 RPLP0 4506667 34423 133 [2] N. D.d
Actin, beta ACTB 16359158 42078 103 [2] 238 [4]
alcohol dehydrogenase beta subunit ADH1B 178098 40665 N. D.d 107 [2]
cathepsin D CTSD 157879206 26511 151 [3] 131 [2]
stomatin STOM 14715077 31958 112 [2] N. D.d
apolipoprotein A-I, isoform CRA_b APOA1 177827 23454 566 [9] 1057 [17]
ribosomal protein L7 RPL7 1335288 29907 170 [2] 75 [1]
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma YWHAG 380765197 28373 169 [2] 96 [1]
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide variant YWHAB 62089104 22563 48 [1] 113 [2]
triosephosphate isomerase 1 TPI1 136066 26894 633 [10] 394 [6]
proteasome subunit alpha type-6 PSMA6 8394076 27838 184 [3] 65 [1]
carbonic anhydrase 1 CA1 4502517 28909 104 [2] 482 [8]
carbonic anhydrase 2 CA2 15080386 29215 N. D.d 237 [4]
azurocidin AZU1 28977 27093 130 [2] N. D.d
phosphoglycerate mutase 1 PGAM1 4505753 28900 91 [2] N. D.d
enoyl-CoA hydratase EHHADH 1922287 31807 107 [2] N. D.d
profilin-1 PFN1 4826898 15216 N. D.d 103 [2]
endoplasmic reticulum protein 29, isoform CRA_b ERP29 119618398 29638 102 [2] N. D.d
pre-serum amyloid P component APCS 337758 25495 337 [5] 318 [5]
peroxiredoxin-6 PRDX6 134254698 25011 342 [6] 299 [5]
MHC class II antigen HLA-DRB1 10185082 30525 N. D.d 183 [3]
MHC class I antigen HLA-DQB 325656872 21947 N. D.d 150 [3]
Rab5c-like protein RAB5C 508285 23781 101 [2] 97 [2]
proteasome subunit beta type-4 PSMB4 22538467 29242 N. D.d 211 [3]
rho GDP-dissociation inhibitor ARHGDIB 56676393 23031 N. D.d 122 [2]

aTheoretical MW

bProtein score assigned by Mascot software is derived from ion scores that are -10*Log [p], where p is the probability that the observed match is a random event

cNumber of peptides matched

dNot determined