Table III. Statistical analysis of the relations between the ratios cystatin C/creatinine, β₂-microglobulin/creatinine, beta-trace protein/creatinine and RBP/creatinine for all non-pregnant patients (men + women) and for non-pregnant patients stratified for their estimated GFR. Medians and p-values are given for the protein-creatinine ratios.

	Gender (male/female)	Cystatin C/creatinine	β2-microglobulin/creatinine	beta-trace protein/creatinine	RBP/creatinine
eGFR mean, men and non-pregnant women
eGFRcystatinC ≈ eGFRcreatinine	32/23	0.014	0.028	0.009	0.518
eGFRcystatinC ≤ 0.6eGFRcreatinine	50/48	0.022	0.052	0.012	0.637
p-value		< 0.0001	< 0.0001	< 0.0001	0.0034
eGFRmean ≤ 40 mL/min/1.73m2
eGFRcystatinC ≈ eGFRcreatinine	11/4	0.012	0.029	0.010	0.448
eGFRcystatinC ≤ 0.6eGFRcreatinine	19/22	0.020	0.045	0.011	0.525
p-value		< 0.0001	0.0002	0.0117	0.1768
eGFRmean 40–60 mL/min/1.73m2
eGFRcystatinC ≈ eGFRcreatinine	7/10	0.015	0.031	0.009	0.557
eGFRcystatinC ≤ 0.6eGFRcreatinine	22/18	0.024	0.053	0.012	0.736
p-value		< 0.0001	< 0.0001	0.0004	0.0031
eGFRmean ≥ 60 mL/min/1.73m2
eGFRcystatinC ≈ eGFRcreatinine	14/9	0.015	0.025	0.009	0.558
eGFRcystatinC ≤ 0.6eGFRcreatinine	9/8	0.024	0.054	0.013	0.658
p-value		< 0.0001	< 0.0001	0.0002	0.1937