Table III.

Laboratory methods used in the studies of HtrA1 in cancer.

Authors/ref.	Involved organ	Methods		mRNA		Protein
		In vitro	In vivo	ISH	PCR	IHC	WB
D’Angelo et al (42)	Nerve cells		√			√	√
Lorenzi et al (43)	Bladder	√	√		√	√	√
Lehner et al (11)	Breast	√	√		√
Yu 2012 et al (44)	Esophagus	√	√		√	√	√
Xia 2013 et al (45)	Esophagus	√	√	√	√	√	√
Catalano et al (12)	Stomach		√			√
Zhu et al (10)	Liver		√			√
Mullany et al (46)	Endometrium	√	√			√
Narkiewicz et al (47)	Endometrium		√		√		√
Bowden et al (48)	Endometrium		√		√	√	√
Zurawa et al (49)	Thyroid		√				√
Baldi et al (9)	Pleural mesothelioma	√	√			√	√
Narkiewicz et al (50)	Ovary		√		√		√
Esposito et al (51)	Lung		√			√
Baldi et al (8)	Skin cells (Malignant melanoma)	√	√			√

ISH, in situ hybridization; PCR, polymerase chain reaction; IHC, immunohistochemistry; WB, western blotting.