Figure 1.

Co-expression networks based on hub genes of RCC from co-expression networks constructed by the (A) STRING database, (B) Pearson’s correlation tests, (C) eB method and (D) wGCNA. Genes (nodes) are connected by edges if their vectors are sufficiently similar. Black edge is associated with a pair of genes under thresholds. RCC, renal cell carcinoma; STRING, Search Tool for the Retrieval of Interacting Genes/Proteins; EB, empirical Bayesian; WGCNA, Weighted Gene Co-expression Network Analysis.