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. 2015 Jun 29;10(6):e0131027. doi: 10.1371/journal.pone.0131027

Table 4. Multiple linear regression models for the association between mean HbA1c (dependent variable), PHQ-9 score and SCOFF positive screening results for eating disorders (independent variables).

Model 1 Model 2 Model 3 Model 4 Model 5
ß (95% CI) p ß (95% CI) p ß (95% CI) p ß (95% CI) p ß (95% CI) p
Male Patients
 PHQ-9 score 0.169 <0.001 0.163 <0.001 0.166 <0.001 0.141 0.006
(0.087; 0.252) (0.080; 0.245) (0.082; 0.251) (0.043; 0.239)
 SCOFF positive 0.815 0.155 0.770 0.115 0.735 0.180 0.738 0.145
(-0.315; 1.946) (-0.191; 1.731) (-0.248; 1.718) (-0.260; 1.737)
 age -0.085 0.631 0.023 0.911
(-0.438; 0.268) (-0.393; 0.440)
 diabetes duration 0.073 0.649 0.017 0.922
(-0.244; 0.389) (-0.332; 0.366)
 BMI -0.019 0.715
(-0.124; 0.085)
 insulin pump therapy 0.220 0.501
 (yes vs. no) (-0.429; 0.868)
 socioeconomic status
 (reference: high)
  low 0.702 0.146
(-0.250; 1.653)
  middle 0.740 0.036
(0.049; 1.432)
 family structure/residence: living …
 (reference: with both parents)
  with mother or father (and her/his partner) 0.063 0.881
(-0.776; 0.903)
  alone or with partner in an apartment -0.045 0.957
(-1.723; 1.632)
Female Patients
 PHQ-9 score 0.069 0.071 0.056 0.165 0.054 0.183 0.035 0.410
(-0.006; 0.143) (-0.024; 0.136) (-0.026; 0.134) (-0.049; 0.119)
 SCOFF positive 0.508 0.143 0.334 0.376 0.351 0.356 0.627 0.137
(-0.175; 1.191) (-0.410; 1.078) (-0.400; 1.102) (-0.203; 1.456)
 age 0.292 0.174 -0.366 0.120
(-0.714; 0.131) (-0.830; 0.097)
 diabetes duration 0.188 0.355 0.193 0.354
(-0.213; 0.589) (-0.219; 0.605)
 BMI -0.060 0.289
(-0.172; 0.052)
 insulin pump therapy 0.004 0.989
 (yes vs. no) (-0.656; 0.665)
 socioeconomic status
 (reference: high)
  low 1.228 0.010
(0.300; 2.156)
  middle 0.410 0.340
(-0.438; 1.259)
 family structure/ residence: living …
 (reference: with both parents)
  with mother or father (and her/his partner) -0.524 0.214
(-1.355; 0.308)
  alone or with partner in an apartment -0.152 0.760
(-1.132; 0.829)
  other -0.210 0.822
(-2.059; 1.638)

Data are presented as regression coefficient β (95% CI) with p-value; separate models for PHQ-9 score and MDS/ODS as independent variables. Model 1: SCOFF (ED) (unadjusted). Model 2: PHQ-9 score (unadjusted). Model 3: SCOFF + PHQ-9 score (unadjusted). Model 4: Model 3 + age + diabetes duration. Model 5: Model 4 + BMI + insulin pump therapy + socioeconomic status + family structure/residence