Table 1.
Minimum inhibitory concentration (MIC) values (μg/mL) obtained for the essential oil of P. neochilus (PN-EO), compounds 1, 2, 3, and 4, and the mixture 1 + 2 + 3 + 4 against selected cariogenic bacteria.
| Microorganisms | PN-EO | CHDa | 1 b | 2 b | 3 b | 4 b | 1 + 2 + 3 + 4 c |
|---|---|---|---|---|---|---|---|
| E. faecalis | 250.0 | 14.8 | >4000 | >4000 | >4000 | >4000 | >4000 |
| S. salivarius | 250.0 | 7.4 | 4000 | 4000 | 4000 | 4000 | 4000 |
| S. mutans | 3.9 | 1.8 | >4000 | >4000 | >4000 | >4000 | 1000 |
| S. mitis | 31.3 | 14.8 | 4000 | 4000 | 4000 | 4000 | 4000 |
| S. sobrinus | 62.5 | 1.8 | >4000 | >4000 | >4000 | >4000 | 4000 |
| S. sanguinis | 62.5 | 7.4 | 4000 | >4000 | >4000 | >4000 | >4000 |
| L. casei | 31.3 | 3.7 | 4000 | 4000 | 4000 | 4000 | 500 |
aChlorhexidine dihydrochloride.
bFor compounds 1, 2, 3, and 4, the concentration of 4000 μg/mL corresponds to 29.4, 29.4, 19.6, and 18.1 mM, respectively.
c 1 + 2 + 3 + 4: mixture of α-pinene, β-pinene, trans-caryophyllene, and caryophyllene oxide.