Table 2.
Uni- and multivariate analysis of factors influencing colorectal liver metastases (CLM) detection at intra-operative ultrasound (IOUS) and contrast-enhanced (CE)-IOUS
| No Nr (%) | Yes Nr (%) | χ2 (P-value) | Logistic regression (P-value) | OR | 95% CI | |
|---|---|---|---|---|---|---|
| New CLM at IOUS | ||||||
| MRI versus CT | ||||||
| MRI | 47 (63) | 28 (37) | .436 | NS | ||
| CT | 29 (56) | 23 (44) | ||||
| PET | ||||||
| No | 26 (74) | 9 (26) | .061 | NS | ||
| Yes | 50 (54) | 42 (46) | ||||
| Multiple CLM (≥3) (pre-operative imaging) | ||||||
| No | 47 (72) | 18 (28) | .010 | .016 | 2.5 | 1.18–5.28 |
| Yes | 29 (47) | 33 (53) | ||||
| Pre-operative CHTa | ||||||
| No | 23 (77) | 7 (23) | .026 | .044 | 2.66 | 1.02–6.94 |
| Yes | 51 (54) | 44 (46) | ||||
| Bright liver | ||||||
| No | 59 (57) | 45 (43) | .128 | NS | ||
| Yes | 17 (74) | 6 (26) | ||||
| Isoechoic CLMb | ||||||
| No | 37 (65) | 20 (35) | .421 | NS | ||
| Yes | 34 (58) | 25 (42) | ||||
| Hyperechoic CLMb | ||||||
| No | 58 (61) | 37 (39) | .942 | NS | ||
| Yes | 13 (62) | 8 (38) | ||||
| Hypoechoic CLMb | ||||||
| No | 47 (59) | 33 (41) | .418 | NS | ||
| Yes | 24 (67) | 12 (33) | ||||
| New CLM at CE-IOUS | ||||||
| MRI versus CT | ||||||
| MRI | 71 (95) | 4 (5) | .698 | NS | ||
| CT | 50 (96) | 2 (4) | ||||
| PET | ||||||
| No | 33 (94) | 2 (6) | .746 | NS | ||
| Yes | 88 (96) | 4 (4) | ||||
| Multiple CLM (≥3) (IOUS) | ||||||
| No | 51 (100) | 0 (0) | .023 | .014 | 1.92 | 1.13–6.43 |
| Yes | 70 (92) | 6 (8) | ||||
| Pre-operative CHTa | ||||||
| No | 30 (100) | 0 (0) | .200 | NS | ||
| Yes | 90 (95) | 5 (5) | ||||
| Bright liver | ||||||
| No | 99 (95) | 5 (5) | .925 | NS | ||
| Yes | 22 (96) | 1 (4) | ||||
| Isoechoic CLMb | ||||||
| No | 56 (98) | 1 (2) | .041 | .049 | 2.84 | 1.72–8.96 |
| Yes | 54 (91) | 5 (9) | ||||
| Hyperechoic CLMb | ||||||
| No | 89 (94) | 6 (6) | .237 | NS | ||
| Yes | 21 (100) | 0 (0) | ||||
| Hypoechoic CLMb | ||||||
| No | 75 (94) | 5 (6) | .435 | NS | ||
| Yes | 35 (97) | 1 (3) |
MRI, magnetic resonance imaging; CT, computed tomography; PET; positron emission tomography; CHT, chemotherapy; OR, odds-ration; CI, confidence interval.
a
Data are not available in two patients.
b
Data are not available in 11 patients.