Table 4.
Effect of methanol extract of M. malabathricum leaves (MEMM), quercitrin and ranitidine on levels of glutathione peroxidase (GTP), glutathione reductsase (GTR) and thiobarbituric acid reactive substances (TBARS) in rats of ethanol-induced gastric tissues
| Experimental groups | GTP (nmol min −1 mg of protein −1 ) | GTR (nmol min −1 mg of protein −1 ) | TBARS (nmol TBARS −1 mg of protein 1 ) |
|---|---|---|---|
| Normal (Untreated) | 316.22 ± 52.77 | 28.37 ± 0.91 | 2.81 ± 0.23 |
| Negative Control (Ethanol) | 127.83 ± 20.84* | 12.74 ± 0.77* | 6.27 ± 0.56* |
| 100 mg/kg Ranitidine + Ethanol | 186.81 ± 26.73# | 14.39 ± 1.96 | 4.13 ± 1.07# |
| 250 mg/kg MEMM + Ethanol | 271.56 ± 41.31# | 15.62 ± 1.01# | 4.29 ± 0.33# |
| 500 mg/kg MEMM + Ethanol | 310.18 ± 30.07# | 18.86 ± 2.34# | 3.01 ± 0.92# |
| 50 mg/kg Qurcitrin + Ethanol | 201.16 ± 13.45# | 17.33 ± 0.84# | 3.17 ± 0.12# |
| 250 mg/kg Qurcitrin + Ethanol | 308.24 ± 22.87# | 25.76 ± 1.41# | 2.25 ± 0.33# |
The results were expressed as mean ± SEM.
*significant at p < 0.05 when compared against the normal (untreated) group using the Student’s t-test.
#significant at p < 0.05 when compared against the negative control (ethanol-treated) group using the ANOVA followed by Dunnett’s test.