Appendix Table 11.
Breakdown of Average Lifetime Costs for Each Strategy in 65 and 75 year old men (values include patient time costs).
| Cohort Costs | Cost($) | Cost ($) |
|---|---|---|
| Age | 65 | 75 |
| Active Surveillance | ||
| Surveillance Costs | ||
| Total Pre-treatment | 6081 | 4886 |
| PSA | 2859 | 2299 |
| Biopsies | 1832 | 1474 |
| Visits | 1390 | 1112 |
| Total Post-treatment | 3204 | 1714 |
| Total | 9285 | 6599 |
| Procedure Costs | ||
| Total | 15688 | 12475 |
| Radical Prostatectomy (if applicable) | 0 | 0 |
| IMRT | 15212 | 12084 |
| IMRT+ADT | 476 | 391 |
| Symptoms and Adverse Effect Treatment Costs | ||
| Underlying symptoms | ||
| Total | 12758 | 9817 |
| While on AS | 896 | 489 |
| After treatment | 11862 | 9327 |
| Surveillance biopsy complications | 55 | 44 |
| Treatment of adverse effects of treatment | ||
| Total | 2108 | 1113 |
| Short Term | ||
| RP | 0 | 0 |
| IMRT | 308 | 242 |
| IMRT+ADT | 1 | 1 |
| Total | 310 | 243 |
| Long Term | ||
| RP | 0 | 0 |
| IMRT | 1756 | 849 |
| IMRT+ADT | 42 | 21 |
| Total | 1798 | 870 |
| Radical Prostatectomy | ||
| Procedure Cost | 12199 | 12118 |
| Symptoms and Adverse Effect Treatment Costs | ||
| Underlying symptoms | 11761 | 9334 |
| Treatment of adverse effects of treatment | ||
| Total | 7824 | 5325 |
| Short Term | 1802 | 1762 |
| Long Term | 6022 | 3563 |
| Surveillance Costs | 6396 | 4287 |
| IMRT | ||
| Procedure Cost | 25569 | 25417 |
| Symptoms and Adverse Effect Treatment Costs | ||
| Underlying symptoms | 12235 | 9550 |
| Treatment of adverse effects of treatment | ||
| Total | 4481 | 3010 |
| Short Term | 687 | 692 |
| Long Term | 3794 | 2317 |
| Surveillance Costs | 6413 | 4308 |
| BT | ||
| Procedure Cost | 12283 | 12213 |
| Symptoms and Adverse Effect Treatment Costs | ||
| Underlying symptoms | 12067 | 9469 |
| Treatment of adverse effects of treatment | ||
| Total | 4619 | 2807 |
| Short Term | 196 | 199 |
| Long Term | 4423 | 2608 |
| Surveillance Costs | 6406 | 4321 |
| Watchful Waiting | ||
| Surveillance Costs | ||
| Total Pre-treatment | 4517 | 3664 |
| PSA | 1860 | 1486 |
| Biopsies | 0 | 0 |
| Visits | 1844 | 1473 |
| Bone Scans | 814 | 706 |
| Total Post-Treatment | 1501 | 799 |
| Total | 6018 | 4463 |
| Procedure Costs | ||
| Total | 4617 | 3319 |
| Radical Prostatectomy | 1596 | 1148 |
| IMRT | 2643 | 1889 |
| BT | 379 | 282 |
| Symptoms and Adverse Effect Treatment Costs | ||
| Underlying symptoms | ||
| Total | 12656 | 9871 |
| While on WW | 1812 | 854 |
| After treatment | 10844 | 9017 |
| Treatment of adverse effects of treatment | ||
| Total | 1228 | 648 |
| Short Term | ||
| RP | 228 | 171 |
| IMRT | 52 | 38 |
| BT | 6 | 4 |
| Total | 280 | 209 |
| Long Term | ||
| RP | 547 | 251 |
| IMRT | 320 | 151 |
| BT | 81 | 38 |
| Total | 948 | 440 |
ABBR: AS: active surveillance; RP: radical prostatectomy; BT: brachytherapy; IMRT: intensity-modulated radiation therapy; WW: watchful waiting; ADT: androgen deprivation therapy