Table 4.

Threshold Analyses of Scenarios in Which the QALE of AS if Equal to or Better Than That of WW^*

Model Parameter	AS Base Case	Threshold Value at Which AS QALE is Equal to or BETTER Than WW QALE
Men aged 65 y
HR for prostate cancer-specific death for treatment vs. AS	1.85	≥7.71
Lifetime probability of being treated on AS, %	78	≤63
Utility of AS at which AS if favored over WW	0.83	≥0.87
Men aged 75 y
HR for prostate cancer-specific death for treatment vs. AS	1.85	≥4.30
Lifetime probability of being treated on AS, %	61	≤42
Utility of AS at which AS if favored over WW	0.83	≥0.84

AS = active surveillance; HR = hazard ratio; QALE = quality-adjusted life expectancy; WW = watchful waiting.

^*WW remains less expensive than AS under every reasonable scenario modeled.