(a).
Enzyme | Food, beverage, or bioactive compounds Food sources in italics |
Type of study | Dosages used and references |
---|---|---|---|
Fish oil | Clinical | 3 × 1 g/d fish oil containing 1098 mg EPA and 549 mg DHA [181] | |
Lycopene Tomatoes, rose hips, guava, watermelon, and papaya [111] |
Clinical | 2 × 15 mg/d lycopene [181] | |
Curcumin Turmeric, curry powder [34] |
In vivo | 200 mg/kg/d curcumin [155] 75 mg/kg/d curcumin [156] 50 mg/kg/d curcumin [157] 200 mg/kg/d curcumin [158] |
|
Cruciferous vegetables | In vivo | 0.5 mg/kg/d sulforaphane [159] Diet of 15% crushed broccoli seed [160] |
|
Garlic | In vivo | 50 and 100 mg/kg/d diallyl disulfide [161] 250 mg/kg/d raw garlic [162] 25 mg/kg S-allyl cysteine [163] |
|
Catechins Tea (especially green tea), cocoa, legumes, and grapes [182] |
In vivo | 5, 15, and 45 mg/kg epicatechin [164] 15 mg/kg epicatechin [165] 20 mg/kg Theaphenon E (95% EGCG) [166] 5, 15, and 30 mg/kg epicatechin [167] |
|
Resveratrol Grapes, wine, peanuts, soy, and itadori tea [32] |
In vivo | 10 mg/kg/d [168] 20 mg/kg/d [169] |
|
Nrf2 | Ginger | In vivo | 100 mg/kg/d [6]-shogaol [170] 10 and 100 mg/kg dried ginger extract [171] |
Purple sweet potato | In vivo | 100 and 200 mg/kg anthocyanin extract from purple sweet potato [118] | |
Isoflavones Soy, kudzu root, and red clover [183] |
In vivo | 80 mg/kg/d soy isoflavones [172] 60 and 120 mg/kg puerarin from kudzu root [173] |
|
Coffee | In vivo | 2.0 mL/d coffee to an average animal weight of 200 g ± 10 g [174] | |
Rosemary | In vivo | 50 and 100 mg/kg carnosic acid [175] 5 mg/animal carnosol extract [176] |
|
Blueberry | In vivo | 200 mg/kg blueberry [166] 0.6 and 10 g/day [177] |
|
Pomegranate | In vivo | 1 and 10 g/kg pomegranate extract [178]: note high doses used | |
Naringenin Citrus [179] |
In vivo | 50 mg/kg/d naringenin [179] | |
Ellagic acid Berries, pomegranate, grapes, walnuts, and blackcurrants [42] |
In vivo | Diet of 0.4% ellagic acid [166] | |
Asthaxanthin Algae, yeast, salmon, trout, krill, shrimp, and crayfish [38] |
In vivo | 15 mg/kg astaxanthin [166] | |
γ-tocopherol Nuts, seeds, whole grains, vegetable oils, and legumes [111] |
In vivo | 20.8 mg/kg γ-tocopherol [180] |