(b).
Enzyme | Food, beverage, or bioactive compounds Food sources in italics |
Type of study | Dosages used and references |
---|---|---|---|
CYP3A | Green tea | In vivo | 45 mL/d/rat (avg. 150 g animal weight) green tea [33] 400 mg/kg green tea extract [71] 100 mg/kg/d green tea extract [56] |
Black tea | In vivo | 54 mL/d/rat (avg. 150 g animal weight) black tea [33] | |
Quercetin Apple, apricot, blueberries, yellow onion, kale, alfalfa sprouts, green beans, broccoli, black tea, and chili powder [47, 48] |
In vivo | 10 and 20 mg/kg [72] | |
| |||
CYP3A2 | Cruciferous vegetables | In vivo | 12 mg/kg/d sulforaphane [57] |
| |||
Grapefruit | Clinical | 200 mL grapefruit juice 3 times daily [74] | |
Resveratrol Grapes, wine, peanuts, soy, and itadori tea [32] |
Clinical | 1 g/d resveratrol [28]: note high dose used | |
CYP3A4 | Garden cress | Clinical | 7.5 g twice daily dose of garden cress seed powder [55] |
Soybean | In vivo | 100 mg/kg soybean extract [7] | |
Kale | In vivo | 2 g/kg/d kale, as freeze-dried kale drink [51] | |
Myricetin Onions, berries, grapes, and red wine [58] |
In vivo | 0.4, 2, and 8 mg/kg myricetin [58] |