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. 2015 Jun 29;10(6):e0131929. doi: 10.1371/journal.pone.0131929

Fig 6. A schematic illustration of the effect of MB on the inhibition of apoptosis and induction of autophagy.

Fig 6

MB induces neuroprotection in neurons following cerebral ischemia through both the apoptotic p53-Bcl-2-Bax signaling pathway and autophagic p53-AMPK-TSC2-mTOR signaling pathway. The arrows show the effect of MB on these pathways.