Table 4.
Treatments | Dose (mg/kg) | Mean survival time (days) | % Increase in mean survival time | Inference |
---|---|---|---|---|
Normal saline | (0.2 mL/mouse) | 9 | – | – |
5-FU | 20 | 19 | 211.11 | Significant activity |
AR-A001 | 100 | 19 | 211.11 | Significant activity |
AR-A004 | 100 | 14 | 155.56 | Significant activity |
5-FU = 5-fluorouracil.
T/C% < 125% = toxic/inactive; T/C% > 125% = significant antileukemic effect.