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Effects of AR-A001 and AR-A004 extracts against L1210 lymphoid leukemia in CDF1 mice.
| Treatments | Dose (mg/kg) | Mean survival time (days) | % Increase in mean survival time | Inference |
|---|---|---|---|---|
| Normal saline | (0.2 mL/mouse) | 9 | – | – |
| 5-FU | 20 | 19 | 211.11 | Significant activity |
| AR-A001 | 100 | 19 | 211.11 | Significant activity |
| AR-A004 | 100 | 14 | 155.56 | Significant activity |
5-FU = 5-fluorouracil.
T/C% < 125% = toxic/inactive; T/C% > 125% = significant antileukemic effect.
