Table 3.

The percentage change (% Change) in antibody concentration at age 7 years when the PFAS concentration is doubled. Results are from multiple linear regressions for PFAS concentrations at age 7 years (6 models shown in row 1--2), structural equations models of latent individual PFAS measured by 5- and 7-year concentrations (6 models shown in row 3–4), and one structural equation model with all three latent PFASs (1 model shown in row 5–6). All models were adjusted for the covariates gender, age, and booster type

		PFOS		PFOA		PFHxS
Antibody	N	% Change	95 % CI	% Change	95 % CI	% Change	95 % CI
Linear regression:
Anti-diphtheria	443	−30.3	−47.3, −7.8	−25.4	−40.9, −5.8	−16.7	−30.8, 0.2
Anti-tetanus	443	−9.1	−32.8, 23.0	−20.5	−38.2, 2.1	−22.3	−36.3, −5.2
SEMa (Additional file 1: Model 1)
Anti-diphtheria	448	−34.3	−52.8, −8.9	−34.7	−52.5, −10.2	−13.9	−27.9, 2.7
Anti-tetanus	448	−16.3	−41.5, 19.3	−38.2	−56.1, −13.0	−18.7	−32.8, −1.7
SEM mutually adjustedb, Additional file 1: Model 2
Anti-diphtheria	448	−26.1	−49.4, 7.9	−26.9	−47.4, 1.5	1.7	−17.7, 25.8
Anti-tetanus	448	18.7	−21.2, 78.7	−29.6	−50.6, 0.4	−15.0	−32.4, 6.8

^aSee Fig. 1. Goodness of fits: χ ²-test P: 0.08–0.88, RMSEA: ≤ 0.01–0.06, CFI: 0.99–1.00, SRMR: 0.01–0.02

^bSee Additional file 1: Figure S2. Goodness of fits: χ ²-test P: ≤ 0.01, RMSEA: 0.06, CFI: 0.99, SRMR: 0.03