Table 7.
Effect of oral treatments with 125–500 mg/kg/day of MIASE on hepatic tissue SOD, CAT, GSH and MDA in post-CCl4-treated rats.
| Group | SOD (U/mg protein) | CAT (U/mg protein) | GSH (U/mg protein) | MDA (U/mg protein) |
|---|---|---|---|---|
| I | 2.74 ± 0.19 | 24.84 ± 1.66 | 0.92 ± 0.07 | 0.10 ± 0.00 |
| II | 1.59 ± 0.17c− | 11.29 ± 0.63c− | 0.48 ± 0.03a− | 0.15 ± 0.03b |
| III | 3.68 ± 0.26c+ | 27.50 ± 1.87c+ | 1.72 ± 0.06c+ | 0.02 ± 0.01f |
| IV | 3.68 ± 0.26c+ | 18.24 ± 1.21b+ | 0.99 ± 0.20a+ | 0.09 ± 0.01e |
| V | 3.92 ± 0.22c+ | 20.71 ± 1.15c+ | 1.25 ± 0.19c+ | 0.11 ± 0.01 |
| VI | 4.07 ± 0.12c+ | 26.45 ± 1.50c+ | 1.72 ± 0.05c+ | 0.08 ± 0.01e |
a− and c− represent significant decreases at p < 0.05 and p < 0.0001, respectively, when compared to Group I values while a+,b+ and c+ represent significant increases at p < 0.05, p < 0.001 and p < 0.0001, respectively, when compared to Group II values. b represents a significant increase at p < 0.001 when compared to Group II values while e and f represent significant decreases at p < 0.001 and p < 0.0001, respectively, when compared to Group II values.