Table 4.
Multivariable Cox Regression analyses for all-cause mortality and AHF related rehospitalization at 5 years in AHF patients (n = 122)
| All-cause mortality | AHF-related reospitalization | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| hFABP | Troponin I | hFABP | Troponin I | |||||||||
| HR | 95 % CI | p Value | HR | 95 % CI | p Value | HR | 95 % CI | p Value | HR | 95 % CI | p Value | |
| Age | 1.056 | 1.025–1.088 | 0.001 | 1.060 | 1.029–1.092 | 0.001 | 1.027 | 0.997–1.058 | 0.079 | 1.032 | 1.002–1.062 | 0.039 |
| Sex | 1.096 | 0.573–2.098 | 0.783 | 0.657 | 0.317–1.362 | 0.259 | 1.354 | 0.651–2.815 | 0.418 | 1.548 | 0.742–3.230 | 0.244 |
| NYHA functional class | 0.942 | 0.619–1.433 | 0.780 | 0.501 | 0.075–3.333 | 0.475 | 1.610 | 1.001–2.592 | 0.049 | 0.798 | 0.059–10.61 | 0.864 |
| Left ventricular function | 1.263 | 0.926–1.724 | 0.141 | 1.450 | 1.040–2.021 | 0.028 | 1.227 | 0.875–1.720 | 0.236 | 1.167 | 0.836–1.628 | 0.364 |
| Coronary artery disease | 0.812 | 0.423–1.561 | 0.532 | 0.893 | 0.461–1.727 | 0.736 | 1.140 | 0.559–2.323 | 0.718 | 1.133 | 0.558–2.302 | 0.731 |
| Diabetes mellitus | 1.163 | 0.622–2.178 | 0.635 | 1.172 | 0.625–2.198 | 0.620 | 1.324 | 0.682–2.570 | 0.408 | 1.202 | 0.623–2.317 | 0.584 |
| Creatinine (mg/dl) | 0.952 | 0.463–1.954 | 0.892 | 1.234 | 0.597–2.547 | 0.571 | 0.400 | 0.159–1.003 | 0.051 | 0.448 | 0.187–1.073 | 0.072 |
| Sodium (mmol/l) | 0.978 | 0.920–1.039 | 0.463 | 0.967 | 0.910–1.026 | 0.264 | 1.113 | 1.023–1.211 | 0.013 | 1.123 | 1.030–1.225 | 0.008 |
| Hemoglobin (g/dl) | 0.836 | 0.701–0.998 | 0.047 | 0.827 | 0.694–0.986 | 0.034 | 0.949 | 0.792–1.139 | 0.576 | 0.934 | 0.780–1.117 | 0.453 |
| ACEI/ARB treatment | 0.919 | 0.498–1.701 | 0.790 | 1.005 | 0.544–1.859 | 0.987 | 1.425 | 0.722–2.812 | 0.307 | 1.501 | 0.758–2.974 | 0.244 |
| Beta-blocker treatment | 0.895 | 0.488–1.644 | 0.721 | 0.826 | 0.451–1.511 | 0.535 | 1.387 | 0.704–2.732 | 0.345 | 1.550 | 0.795–3.023 | 0.198 |
| LogNT-proBNP (ng/l) | 1.207 | 0.911–1.601 | 0.190 | 1.324 | 0.997–1.757 | 0.052 | 0.911 | 0.696–1.192 | 0.496 | 1.015 | 0.780–1.320 | 0.912 |
| hFABP (10 ng/ml) | 0.996 | 0.948–1.047 | 0.873 | - | - | - | 1.073 | 1.018–1.132 | 0.008 | - | - | - |
| Troponin I (μg/l) | - | - | - | 0.789 | 0.567–1.071 | 0.125 | - | - | - | 0.982 | 0.914–1.055 | 0.620 |
The logarithmic function of NT-proBNP and hFABP per every 10 ng/ml change were used in Cox Models. Significant p values (p<0.05) are written in bold type. Dashes indicate non applicable
HR hazard ratio, CI confidence interval