Table 2.
Association of WOMAC function with incident TKA over 30 months, men and women combined
| WOMAC function (0–68) | Knee periods (number) | Number of TKAs (%) | Crude model | Adjusted model (basic covariates*) | Adjusted model (basic covariates plus ipsilateral VAS pain score) | |||
|---|---|---|---|---|---|---|---|---|
| RR (95% CI) | p value | RR (95% CI) | p value | RR (95% CI) | p value | |||
| 0–5 | 3604 | 12 (0.33) | 1.0 | 1.0 | 1.0 | |||
| 6–9 | 1174 | 20 (1.70) | 5.2 (2.3–11.8) | < 0.001 | 3.5 (1.6–7.9) | 0.002 | 3.1 (1.4–7.0) | 0.006 |
| 10–19 | 2439 | 98 (4.02) | 11.6 (5.8–23.1) | < 0.001 | 5.6 (2.8–11.2) | < 0.001 | 4.4 (2.2–8.8) | < 0.001 |
| 20–29 | 1870 | 145 (7.75) | 22.2 (11.3–43.8) | < 0.001 | 8.7 (4.4–17.1) | < 0.001 | 5.4 (2.7–10.8) | < 0.001 |
| 30–39 | 1080 | 125 (11.57) | 33.4 (16.9–65.9) | < 0.001 | 11.8 (5.9–23.4) | < 0.001 | 5.9 (2.9–12.0) | < 0.001 |
| 40–68 | 462 | 62 (13.42) | 39.1 (19.3–79.2) | < 0.001 | 15.5 (7.6–31.8) | < 0.001 | 5.9 (2.8–12.5) | < 0.001 |
| p for linear trend | < 0.001 | < 0.001 | ||||||
* Clinic site, age, body mass index, race, education, Center for Epidemiologic Studies Depression Scale, comorbidity, ipsilateral Kellgren-Lawrence grade, sex; VAS = visual analog scale; RR = relative risk.