Table 5. Comparison of the sensitivity (SN), specificity (SP), positive predictive value (PPV), negative predictive value (NPV), F-measure (F), and accuracy (ACC) between LIDC and the nine other prediction methods for the top 20% of proteins in two different PINs.

Data sets	Methods	SN	SP	PPV	NPV	F-measure	ACC
YDIP_5093	DC	0.35	0.85	0.41	0.81	0.50	0.73
	BC	0.31	0.83	0.35	0.80	0.45	0.71
	NC	0.40	0.86	0.46	0.83	0.54	0.75
	LID	0.39	0.86	0.45	0.83	0.54	0.75
	PeC	0.40	0.86	0.46	0.83	0.55	0.75
	CoEWC	0.41	0.86	0.47	0.83	0.56	0.76
	WDC	0.42	0.86	0.48	0.83	0.56	0.76
	ION	0.41	0.86	0.53	0.84	0.61	0.78
	UC	0.42	0.86	0.48	0.83	0.57	0.76
	LIDC	0.44	0.87	0.50	0.84	0.59	0.77
YMIPS_4546	DC	0.25	0.82	0.28	0.79	0.38	0.69
	BC	0.25	0.81	0.28	0.79	0.38	0.69
	NC	0.28	0.82	0.31	0.80	0.42	0.70
	LID	0.27	0.82	0.30	0.80	0.41	0.70
	PeC	0.30	0.83	0.34	0.80	0.44	0.71
	CoEWC	0.31	0.83	0.34	0.81	0.45	0.71
	WDC	0.30	0.83	0.34	0.81	0.45	0.71
	ION	0.45	0.86	0.49	0.84	0.59	0.77
	UC	0.31	0.83	0.34	0.81	0.45	0.71
	LIDC	0.42	0.86	0.46	0.84	0.56	0.76