Table 1. Summary of DNA copy number aberrations identified in twenty C-TL and twelve G-TL.
| Chromosome | Locus | Aberration Class | C-TL Frequency (n/20) | G-TL Frequency (n/12) |
|---|---|---|---|---|
| 1 | Centromeric Amplification | 1 | 0 | |
| 1 | Interstitial Amplification | 0 | 1 | |
| 1 | Telomeric Amplification | 3 | 1 | |
| 1 | Trisomy | 1 | 0 | |
| 1 | Including Bend6 | Large Interstitial Deletion | 1 | 0 |
| 1 | Including Abl2 | Large Interstitial Deletion | 1 | 0 |
| 2 | Telomeric Amplification | 1 | 0 | |
| 2 | Including Abi1 | Large Interstitial Deletion | 1 | 0 |
| 2 | Notch1 (5ʹ Deletion) | Recurrent Small Deletion | 7 | 5 |
| 2 | Inside Notch1 | Small Interstitial Deletion | 1 | 0 |
| 3 | Centromeric Deletion | 2 | 0 | |
| 3 | Telomeric Deletion | 0 | 1 | |
| 3 | Including Vcam1 | Large Interstitial Deletion | 1 | 0 |
| 4 | Breakpoint at Tal2 | Centromeric Amplification | 0 | 1 |
| 4 | Breakpoint at Cdkn2a | Interstitial Amplification | 1 | 0 |
| 4 | Inside or including Cdkn2a | Small Interstitial Deletion | 5 | 2 |
| 4 | Including Tox | Large Interstitial Deletion | 0 | 1 |
| 4 | Compound Deletions in Pax5 | Large Interstitial Deletion | 0 | 1 |
| 5 | Telomeric Amplification | 1 | 1 | |
| 5 | Telomeric Deletion | 1 | 0 | |
| 5 | Including Rad9b | Large Interstitial Deletion | 0 | 1 |
| 6 | Interstitial Amplification | 1 | 0 | |
| 6 | Trisomy | 0 | 1 | |
| 6 | Breakpoint at Wnt2 | Large Interstitial Deletion | 1 | 0 |
| 6 | Large Interstitial Deletion | 1 | 0 | |
| 7 | Interstitial Amplification | 1 | 0 | |
| 7 | Large Interstitial Deletion | 1 | 0 | |
| 8 | Telomeric Amplification | 0 | 1 | |
| 8 | Large Interstitial Deletion | 1 | 0 | |
| 9 | Interstitial Amplification | 1 | 0 | |
| 9 | Including Suhw4 | Large Interstitial Deletion | 1 | 0 |
| 9 | Breakpoint at Tgfbr2 | Large Interstitial Deletion | 1 | 0 |
| 10 | Interstitial Amplification | 1 | 0 | |
| 10 | Telomeric Amplification | 0 | 1 | |
| 10 | Trisomy | 2 | 2 | |
| 11 | Centromeric Amplification | 0 | 1 | |
| 11 | Centromeric Deletion | 2 | 1 | |
| 11 | Telomeric Amplification | 2 | 1 | |
| 11 | Inside or including Ikzf1 | Small Interstitial Deletion | 5 | 6 |
| 11 | Including Ikzf1 | Large Interstitial Deletion | 4 | 0 |
| 11 | Inside Ikzf1 | Interstitial Amplification | 1 | 0 |
| 12 | Centromeric Amplification | 4 | 1 | |
| 12 | Breakpoint at Sox11 | Centromeric Deletion | 1 | 0 |
| 12 | Upstream of Sox11 | Large Interstitial Deletion | 1 | 0 |
| 12 | Including or Breakpoint at Bcl11b | Telomeric Deletion | 10 | 4 |
| 12 | Inside or including Bcl11b | Large Interstitial Deletion | 5 | 1 |
| 14 | Breakpoint at TCRa/d | Centromeric Deletion | 1 | 1 |
| 14 | Trisomy | 8 | 3 | |
| 15 | Centromeric Amplification | 1 | 1 | |
| 15 | Trisomy | 13 | 8 | |
| 16 | Centromeric Deletion | 3 | 0 | |
| 16 | Telomeric Amplification | 1 | 2 | |
| 16 | Trisomy | 0 | 1 | |
| 16 | Upstream of A2bp1 | Large Interstitial Deletion | 1 | 0 |
| 17 | Telomeric Deletion | 1 | 0 | |
| 17 | Trisomy | 1 | 0 | |
| 17 | Breakpoint at Cdkn1a | Large Interstitial Deletion | 0 | 1 |
| 18 | Centromeric Amplification | 1 | 0 | |
| 19 | Compound Deletions in Pten | Small Interstitial Deletion | 4 | 0 |
| 19 | Inside or including Pten | Small Interstitial Deletion | 2 | 1 |
| 19 | Including Pten | Large Interstitial Deletion | 3 | 0 |
| 19 | Large Interstitial Deletion | 1 | 0 | |
| X | Telomeric Amplification | 1 | 0 | |
| X | Monosomy | 1 | 1 | |
| X | Large Interstitial Deletion | 1 | 0 |
Copy number variations associated with recombination at the TCRβ, TCRγ, TCRα/δ, Skint, IgH, IgLκ and IgLλ loci are omitted for clarity. Where a locus is listed, the feature was observed within this gene, or the feature included this gene, as noted. Where the feature covered multiple genes and was not clearly associated with any one locus, no locus is listed. Although multiple tumours may be listed for any one feature, the precise nature of each copy number change varied between tumours. Where there is more than one of the same type of feature listed for the same chromosome, each feature represents a distinct chromosomal location.