Table 2. The mean levels of MMP-8, -9, MPO, TIMP-1 and the ratios of MMP-8 and -9/TIMP-1 in stimulated saliva from MI and non-MI subjects.
Condition/Biomarker | MI (n = 200) | non-MI (n = 200) | ||
---|---|---|---|---|
Mean ± SD | Mean ± SD | p1 | p2 | |
MMP-8 (ng/mL) | 440 ± 377 | 543 ± 398 | 0.008 | 0.003 |
MMP-9 (ng/mL) | 260 ± 257 | 264 ± 217 | 0.88 | 0.78 |
MPO (ng/mL) | 1637 ± 1386 | 1899 ± 1447 | 0.06 | 0.02 |
TIMP-1 (ng/mL) | 208 ± 119 | 229 ± 129 | 0.08 | 0.09 |
MMP-8/ TIMP-1 | 1.63 ± 2.79 | 1.62 ± 2.48 | 0.99 | 0.60 |
MMP-9/ TIMP-1 | 0.74 ± 1.45 | 0.56 ± 0.81 | 0.12 | 0.20 |
p1 indicates significance of the differences after a bivariate comparison. p2 indicates the significance after compensation for differences in smoking, BOP, PPD 4–5 mm and PPD ≥ 6 mm.