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. 2015 Jul 1;10(7):e0126370. doi: 10.1371/journal.pone.0126370

Table 2. The mean levels of MMP-8, -9, MPO, TIMP-1 and the ratios of MMP-8 and -9/TIMP-1 in stimulated saliva from MI and non-MI subjects.

Condition/Biomarker MI (n = 200) non-MI (n = 200)
Mean ± SD Mean ± SD p1 p2
MMP-8 (ng/mL) 440 ± 377 543 ± 398 0.008 0.003
MMP-9 (ng/mL) 260 ± 257 264 ± 217 0.88 0.78
MPO (ng/mL) 1637 ± 1386 1899 ± 1447 0.06 0.02
TIMP-1 (ng/mL) 208 ± 119 229 ± 129 0.08 0.09
MMP-8/ TIMP-1 1.63 ± 2.79 1.62 ± 2.48 0.99 0.60
MMP-9/ TIMP-1 0.74 ± 1.45 0.56 ± 0.81 0.12 0.20

p1 indicates significance of the differences after a bivariate comparison. p2 indicates the significance after compensation for differences in smoking, BOP, PPD 4–5 mm and PPD ≥ 6 mm.