Table 6. Biomarkers related to smoking and gender of MI patients and non-MI subjects.
Biomarker | MI (n = 200) | non MI (n = 200) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Smoking | Gender | Smoking | Gender | |||||||||
Median (IQR) | Median (IQR) | Median (IQR) | Median (IQR) | |||||||||
Current smokers | Non-smokers | p | Women | Men | p | Current smokers | Non-smokers | p | Women | Men | p | |
MMP-8 | 350 (587) | 275 (536) | 0.23 | 182 (255) | 388 (579) | 0.01 | 463 (602) | 478 (739) | 0.62 | 335 (598) | 487 (633) | 0.02 |
MMP-9 | 233 (235) | 151 (247) | 0.09 | 144 (256) | 189 (246) | 0.31 | 240 (277) | 225 (260) | 0.33 | 203 (325) | 245 (257) | 0.19 |
MPO | 1372 (1747) | 1077 (1168) | 0.16 | 693 (1102) | 1340 (1587) | 0.01 | 1526 (1433) | 1454 (1623) | 0.99 | 1181 (1759) | 1535 (1593) | 0.07 |
TIMP-1 | 191 (127) | 171 (114) | 0.15 | 180 (130) | 187 (125) | 0.39 | 215 (174) | 197 (150) | 0.31 | 198 (173) | 210 (171) | 0.89 |
MMP-8/ TIMP-1 | 0.84 (1.78) | 0.71 (1.79) | 0.59 | 0.33 (0.76) | 0.87 (1.80) | 0.01 | 0.91 (1.59) | 0.93 (1.80) | 0.70 | 0.70 (1.33) | 0.98 (1.62) | 0.08 |
MMP-9/ TIMP-1 | 0.28 (0.65) | 0.21 (0.69) | 0.29 | 0.16 (0.74) | 0.27 (0.60) | 0.21 | 0.29 (0.54) | 0.34 (0.66) | 0.22 | 0.29 (0.74) | 0.32 (0.53) | 0.42 |
Significance of the differences calculated with Mann-Whitney´s U test.