Table 1.

Patient characteristics

	AMKL (FAB M7)							Other AML subtypes
	Total		AML-BFM 98		AML-BFM 04			AML-BFM 98 + 04
	N	(%)	N	(%)	N	(%)	P a	N	(%)	P b
Gender
Male	53	54.6	21	56.8	32	53.3		625	51.3
Female	44	45.4	16	43.2	28	46.7	0.83	594	48.7	0.52
Age, years
<2	64	66.0	24	64.9	40	66.7		241	19.8
2–5	23	23.7	6	16.2	17	28.3		170	13.9
≥6	10	10.3	7	18.9	3	5.0	0.06	808	66.3	<0.001
WBC, 109/L
<20	75	77.3	24	64.9	51	85.0		631	51.8
>20	22	22.7	13	35.1	9	15.0	0.03	587	48.2	<0.001
CNS involvement
No	92	94.8	35	100.0	57	96.6		1036	87.6
Yes	2	2.1	–	–	2	3.4	0.53	147	12.4	<0.001
BM day 15 + 28
≤5 % of blasts	74	77.9	24	66.7	50	84.7		815	71.1
>5 % of blasts	21	21.1	12	33.3	9	15.3	0.05	331	28.9	0.16
Anamnesis
<3 weeks	38	41.8	16	43.2	22	36.7		680	57.2
≥3 weeks	53	58.2	18	48.6	35	48.3	0.51	508	42.8	0.004
Allo HSCT in 1.CR
Yes	18	22.8	9	27.3	9	18.8		113	89.5
No	63	77.8	24	72.7	39	81.3	0.35	962	10.5	<0.001

^aAML-BFM 98 vs. AML-BFM 04

^bAMKL vs. other AML subtypes