Fig 4. Plasmin-treatment of MoDCs suppresses allogeneic lymphocyte proliferation.

MoDCs prepared from four different donors were treated with 100 nM plasmin for 24 h, then washed and incubated with allogeneic PBMCs in triplicate for 4 days. 3H-thymidine incorporation over the last 24 h was taken as a measure of lymphocyte proliferation. Data are shown as mean ± s.e.m. *p<0.05, **p<0.01 and ***p<0.001 by unpaired two-tail Student’s t-test.