Table 7. Regional Increases in rCBF that Differentiate PTSD from TBI using ROI Analysis in Distinguishing TBI from PTSD.
| Brain Region | Group 1: TBI vs PTSD At Rest | Group 1: TBI vs PTSD On-Task | Group 2: TBI vs PTSD At Rest | Group 2: TBI vs PTSD On-Task |
|---|---|---|---|---|
| Limbic | Amygdala | Amygdala | Amygdala | Amygdala |
| Hippocampus | Hippocampus | Hippocampus | Hippocampus | |
| Ant Cingulum | Ant Cingulum | Ant Cingulum | Ant Cingulum | |
| Mid Cingulum | Mid Cingulum | Mid Cingulum | Mid Cingulum | |
| Post Cingulum | Post Cingulum | Post Cingulum | Post Cingulum | |
| Thalamus | Thalamus | Thalamus | Thalamus | |
| Basal Ganglia | Caudate | Caudate | Caudate | Caudate |
| Putamen | Putamen | Putamen | Putamen | |
| Insula | Insula | Insula | Insula | Insula |
| Prefrontal Cortex | Inferior Orbits | Inferior Orbits | Inferior Orbits | Inferior Orbits |
| Operculum | Operculum | Operculum | Operculum | |
| Temporal Lobes | Middle Temporal Lobe | Middle Temporal Lobe | Middle Temporal Lobe | Middle Temporal Lobe |
| Superior Temporal Lobe | Superior Temporal Lobe | Superior Temporal Lobe | Superior Temporal Lobe | |
| Temporal Poles | Temporal Poles | Temporal Poles | Temporal Poles | |
| Cerebellum | Anterior Cerebellum | Anterior Cerebellum | Anterior Cerebellum | Anterior Cerebellum |
PTSD shows increased rCBF in the limbic centers, basal ganglia, insula, prefrontal cortex, temporal lobes, cerebellum, occipital lobe and parietal lobe as compared to TBI both at rest and during a concentration task in Groups 1 and 2 using ROI analysis. Legend for Abbreviations: Ant = Anterior; Mid = Middle; Post = Posterior; Sup = Superior.