Table 2.
Mortality [%] after pretreatments of NEAO and co-application of paraoxon and pralidoxime.
| Groups (G) | POX DOSE (μmol/rat) | 30 min | 1 hour | 2 hours | 3 hours | 4 hours | 24 hours | 48 hours |
|---|---|---|---|---|---|---|---|---|
| G1: POX only | 1/2 | 79/92 | 83/92 | 88/92 | 88/92 | 88/92 | 88/92 | 88/92 |
| G2: PAM before POX | 1/2 | 4/42 | 17/46 | 17/46 | 17/50 | 17/58 | 17/71 | 17/75 |
| G3: NAC before POX | 1/2 | 94/96 | 94/96 | 100/100 | 100/100 | 100/100 | 100/100 | 100/100 |
| G4: NAC before (POX + PAM) | 1/2 | 17/71 | 33/75 | 38/79 | 42/79 | 42/88 | 50/92 | 50/92 |
| G5: (POX + PAM) | 1/2 | 8/75 | 8/79 | 13/79 | 17/79 | 25/79 | 25/83 | 29/83 |
| G6: GSH before (POX + PAM) | 1/2 | 67/46 | 67/67 | 71/92 | 75/96 | 83/90 | 83/96 | 88/96 |
| G7: GSH before POX | 1/2 | 92/83 | 92/92 | 96/92 | 100/92 | 100/96 | 100/96 | 100/96 |
| G8: AA before (POX + PAM) | 1/2 | 58/83 | 63/83 | 75/88 | 79/92 | 96/92 | 96/92 | 96/96 |
| G9: AA before POX | 1/2 | 58/75 | 67/83 | 75/83 | 75/83 | 75/92 | 83/100 | 83/100 |