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. 2015 May 15;6(2):252–266. doi: 10.3390/genes6020252

Figure 1.

Figure 1

Structure and sequence of Geminin. (Top) Diagrammatic representation of a Geminin monomer. Black bars, Cdt1 binding sites; D-box, destruction box required in cis for ubiquitylation; NLS, nuclear localization signal. (Bottom) Sequence alignment of Human, mouse and Xenopus Geminin. Conserved residues are shaded. Mutated residues in GemininAWA, GemininRTGG and GemininKKFEV are indicated.