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. 2015 Jun 11;7(6):2980–2998. doi: 10.3390/v7062756

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© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Median LD₅₀ upon inoculation with rNDVs. Cells were either mock inoculated (not shown; set as 100% viable) or inoculated with rNDV at different m.o.i. (range 0.0001–100). Cytotoxicity was measured after 5 days by LDH assay and LD₅₀ values were calculated. Means and ranges of LD₅₀ calculations are plotted. * = p < 0.05 as compared rNDV-GFP-F₀, rNDV-hIFNβ-F₀ and rNDV-F_3aa compared to rNDV-F₀. # = p < 0.05, rNDV-F_3aa compared to rNDV-hIFNβ-F₀. ^ = p < 0.05 rNDV-F3_aa compared to rNDV-NS1-F₀.