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. 2015 Jul 2;9:173. doi: 10.3389/fnbeh.2015.00173

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Copyright © 2015 Wakabayashi and Kiyatkin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Changes in NAc [glucose] induced by intra-gastric glucose injections. Panel (A) shows overall changes in NAc glucose for 60 min after intra-gastric glucose injections (4 and 8 ml) and after drinking (mean 5.17 ml) in the same rats (30-s bins). (B) compares the duration and magnitude of the response (as area under the curve) for each condition in (A), where there was an overall main effect (One-Way RM ANOVA, F_(2,4) = 9.45, p < 0.05), and the difference between 8 mg and drinking approached significance p = 0.051. (C) compares the initial response between all rats when they began drinking as a result of the tube presentation, and when a subset of rats received an intragastric injection of glucose (4 and 8 mg), relative to the pre-presentation and pre-injection baseline, respectively. During this time interval the response to a 4 and 8 ml intragastric injection was not significantly different, and was combined. For clarity, error bars not shown.