Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Calcitriol effects in the tumor microenvironment. Calcitriol, either activated from 25OHD in the kidney or intratumorally, acts up-regulating (green arrow) or down-regulating (red arrow) different factors that result in the indicated final biological effects. PGs, prostaglandins; 15-PGDH, 15-hydroxyprostaglandin dehydrogenase; COX-2, cyclooxygenase-2; TNF-α, tumor necrosis factor-α; IL-6, interleukin 6; PDF, prostate deriver factor.
