Table 2. Linear Regression Analysis results between global cognition, attention, visuospatial and memory scores and glycemic variability parameters.
Variables | Statistical parameters | MMSE | Digit Span | RCFT | VLT (delayed recall) | VLT (recognition) |
---|---|---|---|---|---|---|
FBS_SD* | B | -0.017 | -0.014 | -0.024 | -0.147 | -0.009 |
95% CI | -0.042–0.008 | -0.029–0.002 | -0.060–0.013 | -0.393–0.099 | -0.025–0.008 | |
FBS_CV* | B | -0.028 | -0.023 | -0.037 | -0.205 | -0.015 |
95% CI | -0.066–0.010 | -0.046–0.001 | -0.093–0.018 | -0.579–0.169 | -0.040–0.010 | |
PP2_SD** | B | -0.017 | -0.007 | -0.032 | -0.223 | -0.005 |
95% CI | -0.038–0.004 | -0.022–0.007 | -0.064–0.001 | -0.437–-0.008 | -0.019–0.010 | |
PP2_CV** | B | -0.036 | -0.012 | -0.072 | -0.482 | -0.010 |
95% CI | -0.079–0.007 | -0.041–0.018 | -0.137–-0.007 | -0.918–-0.045 | -0.040–0.020 | |
HbA1c_SD*** | B | -1.032 | -0.536 | -1.118 | -1.260 | -0.268 |
95% CI | -1.773–-0.291 | -1.016–-0.056 | -2.242–0.006 | -8.874–6.354 | -0.780–0.245 | |
HbA1c_CV*** | B | -0.093 | -0.046 | -0.111 | -0.051 | -0.030 |
95% CI | -0.154–-0.032 | -0.087–-0.006 | -0.204–-0.017 | -0.689–0.587 | -0.073–0.012 |
B (regression coefficient), CI (confidence interval). The analysis was adjusted for hypertension, hyperlipidemia, current smoking, and mean glucose parameters. For example, SD or CV of FBS glucose values were adjusted for mean FBS values.
*mean fasting glucose
**mean postprandial 2 hour glucose
***mean glycated hemoglobin