Skip to main content
. 2015 Jul 1;10(7):e0124451. doi: 10.1371/journal.pone.0124451

Table 3. Statin Effects on Aggression in Men.

OASMa Change, Comparing Statin Group to Placebo.

Retaining Outliers
Baseline OASMa Statins Simvastatin Pravastatin
N Mean (SD) 95% CI P N Mean (SD) 95% CI P N Mean (SD) 95% CI P
All 664 -0.91 (0.50) -1.9, 0.07 0.070 443 -0.79 (0.59) -2.0, 0.37 0.18 441 -1.0 (0.49) -2.0, -0.06 0.038
OASMa = 0 339 -0.43 (0.21) -0.84, -0.02 0.038 226 -0.46 (0.27) -0.99, 0.07 0.090 242 -0.41 (0.25) -0.90, 0.09 0.10
OASMa > 0 325 -0.90 (1.0) -2.9, 1.1 0.38 217 -0.51 (1.2) -2.8, 1.8 0.66 199 -1.4 (1.0) -3.4, 0.65 0.18
Excluding Outliers (N = 3 outliers)
Baseline OASMa Statins Simvastatin Pravastatin
N Mean (SD) 95% CI P N Mean (SD) 95% CI P N Mean (SD) 95% CI P
All 661 -1.3 (0.39) -2.0, -0.53 0.0009 441 -1.4 (0.43) -2.2, -0.53 0.0015 440 -1.2 (0.46) -2.1, -0.31 0.0083
OASMa = 0 339 -0.43 (0.21) -0.84, -0.02 0.038 226 -0.46 (0.27) -0.99, 0.07 0.090 242 -0.41 (0.25) -0.90, 0.09 0.10
OASMa > 0 322 -1.6 (0.76) -3.1, -0.16 0.030 215 -1.6 (0.80) -3.1, 0.03 0.054 198 -1.8 (0.93) -3.6, 0.07 0.060

CI = confidence interval; OASMa = Overt-Aggression-Scale-Modified–Aggression-Subscale; SD = standard deviation.