Table 5. Men, Stratified at Age 40.

(Note larger number of men in the older group.)

	Placebo		Statin			Simvastatin			Pravastatin
	Mean (SD)	95%CI	Mean (SD)	95%CI	P vs placebo	Mean (SD)	95%CI	P vs placebo	Mean (SD)	95%CI	P vs placebo
Δ OASMa Age ≤ 40 N = 92	0.036 (4.4)	-1.7, 1.8	-2.3 (5.4)	-3.6, -0.95	0.047	-1.7 (4.6)	-3.3, -0.11	0.14	-3.0 (6.2)	-5.4, -0.67	0.037
Δ OASMa Age > 40 N = 569	0.24 (4.5)	-0.40, 0.89	-0.86 (4.6)	-1.3, -0.39	0.007	-1.0 (4.5)	-1.7, -0.40	0.005	-0.68 (4.8)	-1.4, 0.005	0.053
P, difference younger vs older	0.99		0.026			0.59			0.020

CI = confidence interval; OASMa = Overt-Aggression-Scale-Modified–Aggression-Subscale; SD = standard deviation. Magnitude of effect (coefficient) is larger among men under 40, in each statin group. However, there are approximately 6 times as many participants in the over 40 vs the under 40 category, providing greater significance in the simvastatin and statin groups for those age over 40 years, despite smaller effect sizes. Last-on-treatment-value-carried-forward analysis. Excludes the 3 outliers.