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. 2015 Jul 1;10(7):e0124451. doi: 10.1371/journal.pone.0124451

Table 8. Sleep Problems Predict Aggression in Men on Simvastatin and Combined Statins.

Change in Sleep Problems Baseline Sleep Problems
Beta ± SE 95% CI P Beta ± SE 95% CI P
On Placebo N = 188 0.39 ± 0.50 -0.59, 1.4 0.43 -0.16 ± 0.12 -0.39, 0.068 0.17
On Pravastatin N = 179 0.21 ± 0.62 -1.0, 1.4 0.74 0.082 ± 0.13 -0.17, 0.34 0.53
On Statins N = 363 2.2 ± 0.55 1.1, 3.3 <0.001 0.23 ± 0.13 -0.035, 0.49 0.089
On Simvastatin N = 184 3.3 ± 0.83 1.7, 4.9 <0.001 0.38 ± 0.23 -0.068, 0.83 0.096

Beta = regression coefficient; CI = confidence interval; SE = standard error. Regression analysis assessing prediction of change in aggression by self-rating of change in sleep problems, stratified by treatment arm, adjusted for baseline and change in sleep problems; and baseline aggression (Overt-Aggression-Scale-Modified–Aggression-Subscale).